Tardivex is a prescription treatment proven to reduce TD that’s always one capsule, once daily.

It is not known if Tardivex is safe and effective in children.

Do not take Tardivex if you are allergic to valbenazine or any of the ingredients in Tardivex

Tardive dyskinesia (TD) is persistent, uncontrolled body movements. TD movements can occur anywhere in the body:

• Face (mouth, lips, tongue, jaw, eyes)
• Upper body (arms, torso)
• Hands/fingers
• Legs
• Feet/toes

You may have been prescribed certain mental health medicines (antipsychotics) to treat a condition such as:

• Depression
• Bipolar disorder
• Schizophrenia/​schizoaffective disorder
• Anxiety disorder

Certain prescription medicines (metoclopramide and prochlorperazine) used to treat gastrointestinal disorders may also cause TD.

Current research suggests that Tardivex helps by correcting abnormal dopamine signaling; however, how Tardivex works to treat TD is not fully understood.

• Dopamine is a chemical in the brain that helps control movement
• TD may be caused by too much dopamine signaling in the brain
• Tardivex is believed to reduce extra dopamine signaling

Tardivex is used to treat adults with TD in the face, tongue, and other body parts. Adults with mild, moderate, and severe uncontrollable movements of TD should talk to their healthcare provider about Tardivex.

Tardivex (Valbenazine) is clinically proven for reducing TD in adults at 6 weeks.^* Most people saw results in just 2 weeks.^†

^*Tardivex (Valbenazine) was studied in a 6-week clinical trial. A total of 234 people participated in the study. Results were based on 79 people taking the recommended dose of 80 mg.

^†In a 6-week clinical study. Post-clinical evaluation of 149 patients who took 40 mg and/or 80 mg during the first 2 weeks; 64% had at least a 1-point reduction on an uncontrollable movements severity scale.

In a clinical study, psychiatric status remained stable overall in people taking Tardivex for TD, including those who were also taking medicine for:

• Depression
• Bipolar disorder
• Schizophrenia/​schizoaffective disorder
• Anxiety disorder

People taking Tardivex for TD can stay on their current dose of most mental health medicines.

Tardivex (Valbenazine) continued to show TD improvement with continued use. In a long-term study, more than half of people taking Tardivex (Valbenazine)  saw no or minimal movements for each body part after 48 weeks of treatment with Tardivex (Valbenazine).*

*In a post-clinical study evaluation of the KINECT 4 trial, 59% (61/103) of people who completed the trial taking Tardivex (Valbenazine) (40 mg and 80 mg) achieved a score of 1 or less for each body part measured with AIMS at Week 48. The results are descriptive in nature.