Tardive dyskinesia (TD) is a movement disorder that can develop as a side effect of taking certain medications, most commonly antipsychotic drugs. These medications are used to treat mental health conditions such as schizophrenia and bipolar disorder.

TD causes involuntary movements of the face, body, or both. These movements can be repetitive, jerky, or twisting. They can affect the facial muscles, tongue, jaw, limbs, and trunk.

Tardive dyskinesia (TD): Persistent, uncontrolled body movements

Don’t ignore persistent, uncontrollable body movements that could be TD.

Have you experienced any of the following uncontrollable
or involuntary movements?

TD movements can occur anywhere in the body. Watch the videos to see what TD symptoms can look like.

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TD is unlikely to get better on its own, but you can take control by talking with your healthcare provider about your movements right away. Take the first step: Understand the cause of your uncontrollable movements and learn about treatment.

TD is a distinct condition and different from other drug-induced movement disorders. How it is treated may be different, too.

What medicines can cause tardive dyskinesia (TD)?

You may have been prescribed certain mental health medicines (antipsychotics) to treat one of these conditions:

  • Depression
  • Bipolar disorder
  • Schizophrenia/​schizoaffective disorder
  • Anxiety disorder

Certain prescription medicines used to treat gastrointestinal disorders may also cause TD.

Medications that may cause TD

If you are taking or have taken any of the following medications and are experiencing uncontrolled movements, it’s important to share this information with your healthcare provider. Understanding your treatment history can help your healthcare provider determine if your movements may be TD.

First-generation antipsychotics

  • Chlorpromazine 
  • Molindone
  • Fluphenazine 
  • Loxapine 
  • Haloperidol 
  • Perphenazine 
  • Thioridazine 
  • Thiothixene 
  • Trifluoperazine 

Second-generation antipsychotics

  • Aripiprazole 
  • Asenapine 
  • Brexpiprazole 
  • Cariprazine 
  • Clozapine 
  • Iloperidone
  • Lumateperone 
  • Lurasidone 
  • Olanzapine 
  • Paliperidone 
  • Quetiapine 
  • Risperidone 
  • Ziprasidone 

Other medicines that may cause TD

  • Prochlorperazine 
  • Promethazine 
  • Trimethobenzamide 
  • Thiethylperazine 
  • Metoclopramide 

For educational purposes only. Not intended as an exhaustive list of medications that may cause TD. Be sure to discuss any specific questions or concerns with your healthcare provider.

With Tardivex, you can keep taking most mental health medicines.

If you are currently taking antipsychotic medicine, do not stop, adjust, or switch your medicine without talking to your healthcare provider.

Continue taking your medicine as prescribed and be sure to talk to your healthcare provider about TD and FDA-approved treatments, like Tardivex.

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